{"id":582,"date":"2019-07-07T18:02:40","date_gmt":"2019-07-07T09:02:40","guid":{"rendered":"https:\/\/info.zanet.biz\/?p=582"},"modified":"2019-07-09T17:34:04","modified_gmt":"2019-07-09T08:34:04","slug":"integrating-cost-effectiveness-evidence-into-clinical-practice-guidelines","status":"publish","type":"post","link":"https:\/\/info.zanet.biz\/?p=582","title":{"rendered":"…integrating cost effectiveness evidence into clinical practice guidelines"},"content":{"rendered":"\n

Guidelines and Economists Network International ( GENI<\/a> )\u3068\u3044\u3046\u56fd\u969b\u7684\u7d44\u7e54\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u306eAgenda<\/a>\u8ab2\u984c\u306f\u3001<\/p>\n\n\n\n

” To facilitate the effective integration of Clinical Practice Guidelines (CPGs), economic and clinical evidence into national decision making and clinical practice in the health sector, especially hospitals and primary care. “<\/p>\n\n\n\n

\u3059\u306a\u308f\u3061\u300c \u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3001\u7d4c\u6e08\u7684\u304a\u3088\u3073\u81e8\u5e8a\u7684\u30a8\u30d3\u30c7\u30f3\u30b9\u3092\u7279\u306b\u75c5\u9662\u3068\u30d7\u30e9\u30a4\u30de\u30ea\u30b1\u30a2\u306e\u5065\u5eb7\u30bb\u30af\u30bf\u30fc\u3067\u306e\u533b\u7642\u3068\u56fd\u30ec\u30d9\u30eb\u306e\u610f\u601d\u6c7a\u5b9a\u306e\u305f\u3081\u306b\u52b9\u7387\u7684\u306b\u7d71\u5408\u3059\u308b\u3053\u3068\u3092\u4fc3\u9032\u3059\u308b\u3053\u3068 \u300d\u3067\u3059\u3002\u3053\u3053\u3067\u306fEconomic evidence\u3068Clinical evidence\u3068\u3044\u3046\u8a00\u8449\u304c\u4f7f\u308f\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

GENI\u306e Chair: Michael Drummond (UK)    CEO: Kathryn M. Antioch (Australia) \u3068Board Members: Louis Niessen (USA) \u3001 Hindrik Vondeling (Denmark) \u3089\u306e\u8ad6\u6587\u304c2017\u5e74\u306b\u767a\u8868\u3055\u308c\u3066\u304a\u308a\u3001\u201dEconomic evidence”\u3092\u201dClinical Practice Guideline”\u3068”National decision making”\u306b\u3069\u306e\u3088\u3046\u306b\u53d6\u308a\u5165\u308c\u308b\u304b\u306b\u3064\u3044\u3066\u3001\u30aa\u30fc\u30b9\u30c8\u30e9\u30ea\u30a2\u3067\u306e\u4f53\u9a13\u3092\u8e0f\u307e\u3048\u3066\u3001\u8ff0\u3079\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\u3053\u3061\u3089\u306e\u8ad6\u6587\u3067\u3059\u3002 Antioch KM, Drummond MF, Niessen LW, Vondeling H: International lessons in new methods for grading and integrating cost effectiveness evidence into clinical practice guidelines. Cost Eff Resour Alloc 2017;15:1 DOI 10.1186\/s12962-017-0063-x. PMID: 28203120<\/a> <\/p>\n\n\n\n

Economic evidence\u306fCost-effectiveness analysis (CEA) thresholds, Opportunity cost, Willingness-to-pay (WTP)\u306b\u95a2\u3059\u308b\u3082\u306e\u3067\u3059\u3002\u305f\u3060\u3057\u3001End-of-life therapies\u306f\u7279\u5225\u306e\u8003\u616e\u304c\u5fc5\u8981\u3068\u3055\u308c\u307e\u3059\u3002\u3055\u3089\u306b\u3001”Involvement time, logistics, innovation price, price sensitivity, substitutes and complements, absenteeism and presentism\u306b\u95a2\u308f\u3063\u3066\u304d\u307e\u3059\u3002<\/p>\n\n\n\n

Economic evidence\u306e\u30b0\u30ec\u30fc\u30c7\u30a3\u30f3\u30b0\u306b\u306fThe Consolidated Guidelines for the Reporting of Economic Evaluations (CHEERS) 24 item check list\u3068the Drummond ten-point check list\u304a\u3088\u3073\u7d50\u679c\u3092\u30b9\u30b3\u30a2\u5316\u3059\u308b\u305f\u3081\u306e\u8cea\u554f\u7968\u3092\u7528\u3044\u308b\u3053\u3068\u3092\u63d0\u6848\u3057\u3066\u3044\u307e\u3059\u3002\uff08CHEERS\u3068\u305d\u306e\u65e5\u672c\u8a9e\u8a33\u306b\u3064\u3044\u3066\u306f\u5225\u306e\u6295\u7a3f<\/a>\u3067\u7d39\u4ecb\u3057\u307e\u3057\u305f\uff09<\/p>\n\n\n\n

\u3053\u306e\u8ad6\u6587\u306eTable 1 Assessing CEA evidence using shadow prices in Australia: NHMRC*\u3067\u306fRanking of evidence on costs\u3068Ranking of evidence on effects\u306e\u7d44\u307f\u5408\u308f\u305b\u3067\u3001\u751f\u5b58\u5e74\u3042\u305f\u308a\u306e\u8cbb\u7528(\uff04\uff09\u306b\u3088\u3063\u3066\u63a8\u5968\u3059\u308b\/\u63a8\u5968\u3057\u306a\u3044\u3068\u3044\u3046\u5224\u5b9a\u306e\u57fa\u6e96\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\uff08*National Health and Medical Research Council\uff09<\/p>\n\n\n\n

\u305d\u3057\u3066\u3001”Priority setting remains essential and trade-off decisions between policy criteria can be based on MCDA, both in evidence based clinical medicine and in health planning.” \u3059\u306a\u308f\u3061\u3001\u300c\u512a\u5148\u5ea6\u306e\u8a2d\u5b9a\u306f\u5fc5\u9808\u3067\u3042\u308a\u3001\u65b9\u91dd\u57fa\u6e96\u306e\u9593\u306e\u30c8\u30ec\u30fc\u30c9\u30aa\u30d5\u306e\u3042\u308b\u610f\u601d\u6c7a\u5b9a\u306fMCDA\uff08Multi-Criteria Decision Analysis)\u3092\u3088\u308a\u3069\u3053\u308d\u306b\u3067\u304d\u308b\u3067\u3042\u308d\u3046\u300d\u3068\u8ff0\u3079\u3066\u3044\u307e\u3059\u3002MCDA\u306b\u3064\u3044\u3066\u306fISPOR\u306eGood Practice Guidelines for conduction MCDA\u306e\u8ad6\u6587\u3001Thokala P 2016<\/a>\u3068Marsh K 2016<\/a>\u304c\u5f15\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002\uff08\u4ee5\u524d\u306e\u6295\u7a3f<\/a>\u3067\u7d39\u4ecb\u3057\u307e\u3057\u305f\u3002\uff09<\/p>\n\n\n\n

Willingness to pay per QALY\u307e\u305f\u306fLYG (life years gained)\u306e\u53d7\u3051\u5165\u308c\u53ef\u80fd\u306a\u6700\u5927\u5024(\u95be\u5024\uff09\u3092\u8a2d\u5b9a\u3059\u308b\u3053\u3068\u3067\u3001Cost-Effectiveness Analysis (CEA)\u306eDecision rule\u3092\u8a2d\u5b9a\u3067\u304d\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u8ff0\u3079\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u6700\u5927\u5024\u306f\u3001\u60a3\u8005\u3068\u5bb6\u65cf\u306eQOL, \u751f\u5b58\u306e\u6539\u5584\u3001\u6a5f\u80fd\u7684\u72b6\u614b\u3001\u91cd\u7be4\u3067\u307e\u308c\u3067\u4e88\u9632\u53ef\u80fd\u3067\u3042\u308b\u3044\u306f\u82e5\u5e74\u3067\u6c38\u7d9a\u7684\u306a\u52b9\u679c\u306b\u3064\u306a\u304c\u308b\u304b\u3001\u4ed6\u306e\u9078\u629e\u80a2\u304c\u306a\u3044\u3001\u305d\u306e\u4ecb\u5165\u304c\u5e73\u7b49\u306e\u898b\u5730\u304b\u3089\u4ed6\u306e\u30bb\u30af\u30b7\u30e7\u30f3\u3078\u306e\u6709\u5bb3\u306a\u6d41\u308c\u3092\u9632\u6b62\u3067\u304d\u308b\u3001\u306a\u3069\u306e\u9805\u76ee\u3092\u691c\u8a0e\u3057\u305f\u3046\u3048\u3067\u3001\u59a5\u5f53\u6027\u304c\u691c\u8a0e\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n

\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u4f5c\u6210\u8005\u306f\u6700\u65b0\u306eCost-effective methodology\u3092\u77e5\u308b\u5fc5\u8981\u304c\u3042\u308a\u3001NICE\u306eReference Case\u306f\u305d\u306e\u4e00\u3064\u3067\u3042\u308b\u3053\u3068\u304c\u8ff0\u3079\u3089\u308c\u3066\u3044\u307e\u3059\u3002NICE\u306e\u533b\u7642\u7d4c\u6e08\u8a55\u4fa1\u306b\u3064\u3044\u3066\u306f\u4ee5\u524d\u306e\u6295\u7a3f<\/a>\u3067\u7d39\u4ecb\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

\u307e\u305f\u3001International Health Economists Association \uff08iHWA<\/a> \uff09\u3068\u3044\u3046\u7d44\u7e54\u304c\u3042\u308a\u30012019\u5e747\u670813-17\u65e5\u30b9\u30a4\u30b9Basel\u3067\u5b66\u4f1a\u304c\u958b\u50ac\u3055\u308c\u307e\u3059\u3002\u305d\u306e\u30df\u30c3\u30b7\u30e7\u30f3\u306f\u4ee5\u4e0b\u306e\u3068\u304a\u308a\u3067\u3059\u3002\u533b\u7642\u7d4c\u6e08\u5b66\u306e\u767a\u5c55\u304c\u5927\u304d\u306a\u76ee\u7684\u306e\u3088\u3046\u3067\u3059\u3002<\/p>\n\n\n\n

“iHEA\u2019s mission is to:    Increase communication among health economists;    Foster a higher standard of debate in the application of economics to health and health care systems; and    Assist young researchers at the start of their careers. “<\/p>\n\n\n\n

\u3055\u3066\u3001MCDA\u306b\u3064\u3044\u3066\u3067\u3059\u304c\u3001\u533b\u7642\u7d4c\u6e08\u5b66\u7684\u306a\u8a55\u4fa1\u306e\u7d50\u679c\u3068\u81e8\u5e8a\u7684\u306a\u52b9\u679c\u306e\u8a55\u4fa1\u306f\u7570\u306a\u308b\u5c3a\u5ea6\u304c\u7528\u3044\u3089\u308c\u3066\u3044\u308b\u306e\u3067\u3001MCDA\u3067\u30c8\u30ec\u30fc\u30c9\u30aa\u30d5\u306e\u3042\u308b\u8907\u6570\u306e\u8a55\u4fa1\u9805\u76ee\u306b\u542b\u3081\u3066\u8a55\u4fa1\u3057\u4ecb\u5165\u3092\u6bd4\u8f03\u3059\u308b\u306e\u306f\u30ef\u30f3\u30b9\u30c6\u30c3\u30d7\u3067\u306f\u3067\u304d\u307e\u305b\u3093\u3002\u3084\u306f\u308a\u30b9\u30b3\u30a2\u5316\u306e\u30b9\u30c6\u30c3\u30d7\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

Guidelines and Economists Network International ( GENI )\u3068\u3044\u3046\u56fd\u969b\u7684\u7d44\u7e54\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u306eAgenda\u8ab2\u984c\u306f\u3001 ” To facilitate the e … “…integrating cost effectiveness evidence into clinical practice guidelines” \u306e<\/span>\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5,4],"tags":[],"class_list":["post-582","post","type-post","status-publish","format-standard","hentry","category-cpg","category-cea"],"_links":{"self":[{"href":"https:\/\/info.zanet.biz\/index.php?rest_route=\/wp\/v2\/posts\/582","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/info.zanet.biz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/info.zanet.biz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/info.zanet.biz\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/info.zanet.biz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=582"}],"version-history":[{"count":6,"href":"https:\/\/info.zanet.biz\/index.php?rest_route=\/wp\/v2\/posts\/582\/revisions"}],"predecessor-version":[{"id":590,"href":"https:\/\/info.zanet.biz\/index.php?rest_route=\/wp\/v2\/posts\/582\/revisions\/590"}],"wp:attachment":[{"href":"https:\/\/info.zanet.biz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=582"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/info.zanet.biz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=582"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/info.zanet.biz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=582"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}