{"id":369,"date":"2019-03-19T11:58:32","date_gmt":"2019-03-19T02:58:32","guid":{"rendered":"https:\/\/info.zanet.biz\/?p=369"},"modified":"2019-03-19T12:03:03","modified_gmt":"2019-03-19T03:03:03","slug":"who-handbook-for-guideline-development","status":"publish","type":"post","link":"https:\/\/info.zanet.biz\/?p=369","title":{"rendered":"WHO Handbook for Guideline Development"},"content":{"rendered":"\n

WHO\u306f\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u4f5c\u6210\u306e\u65b9\u6cd5\u3068\u3057\u3066GRADE\u30a2\u30d7\u30ed\u30fc\u30c1\u30922007\u5e74\u304b\u3089\u63a1\u7528\u3057\u3066\u3044\u307e\u3059\u3002 WHO Handbook for Guideline Development<\/a> \u306f2nd edition\u304c2014\u5e74\u306b\u767a\u8868\u3055\u308c\u3066\u3044\u307e\u3059\u30029\u7ae0\u306eEvidence assessment\u3067\u4ee5\u4e0b\u306e\u69d8\u306b\u8ff0\u3079\u3089\u308c\u3066\u3044\u307e\u3059\u3002”WHO uses the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach to assess the quality of a body of evidence, and to develop and report recommendations. “<\/p>\n\n\n\n

Handbook\u306e\u4e2d\u3067\u3001\u5f15\u7528\u3055\u308c\u3066\u3044\u308bMcMaster\u5927\u5b66\u306eGRADE\u306e\u30b5\u30a4\u30c8\u3067\u3059\u3002
GRADE Online Learning Modules [website<\/a>]. Ontario: McMaster University; 2014 .
J Clin Epid\u306b\u767a\u8868\u3055\u308c\u3066\u3044\u308bGRADE working group\u306e\u8ad6\u6587\u306e\u30ea\u30b9\u30c8\u3078\u306e\u30ea\u30f3\u30af\u3082\u5f15\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002
GRADE series in the Journal of Clinical Epidemiology [website<\/a>]. Maryland Heights: Elsevier Inc.;\u00a0
\u30a6\u30a7\u30d6\u30c4\u30fc\u30ebGRADEpro GDT\u3078\u306e\u30ea\u30f3\u30af\u3067\u3059\u3002
GRADEpro Guideline Development Tool [website<\/a>]. Ontario: McMaster University and Evidence Prime Inc.; 2014.

2009\u5e74\u306b\u306f WHO\u306eGRADEprofiler help<\/a>\u304c\u767a\u8868\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u3002
<\/p>\n\n\n\n

\u305d\u306e\u5f8c\u30012016\u5e74\u306b14\u300115\u300116\u7ae0\u304c\u8ffd\u52a0\u3067\u767a\u8868\u3055\u308c\u3066\u3044\u307e\u3059\u3002
14. Strong recommendations when the evidence is low quality<\/a>.
15. Using evidence from qualitative research to develop WHO guidelines<\/a>.
16. Decision-making for guideline development at WHO<\/a>. <\/p>\n\n\n\n

WHO\u304c\u4f5c\u6210\u3057\u305f\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306b\u3064\u3044\u3066GRADE\u30a2\u30d7\u30ed\u30fc\u30c1\u306e\u9806\u5b88\u72b6\u6cc1\u306b\u3064\u3044\u3066\u8a55\u4fa1\u3057\u305f\u8ad6\u6587\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u306e\u6982\u7565\u3092\u7d39\u4ecb\u3057\u307e\u3059\u3002<\/p>\n\n\n\n

Alexander PE, Bero L, Montori VM, Brito JP, Stoltzfus R, Djulbegovic B, Neumann I, Rave S, Guyatt G: World Health Organization recommendations are often strong based on low confidence in effect estimates. J Clin Epidemiol 2014;67:629-34. PMID: 24388966<\/a>
WHO\u306eCPG\u306e456\u4ef6\u306e\u63a8\u5968\u306e\u3046\u3061\u5f37\u3044\u63a8\u5968289\u4ef6\u3067\u305d\u306e95\u4ef6\uff0833\uff05)\u306fC\u300122.5\uff05\u306fD\u306e\u30ec\u30d9\u30eb\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u306b\u57fa\u3065\u3044\u3066\u3044\u305f\u3002<\/p>\n\n\n\n

Nasser SM, Cooke G, Kranzer K, Norris SL, Olliaro P, Ford N: Strength of recommendations in WHO guidelines using GRADE was associated with uptake in national policy. J Clin Epidemiol 2015;68:703-7. PMID: 25578218 <\/a>
WHO\u306eCPG\u306e\u63a8\u5968\u306e\u5404\u56fd\u3067\u306e\u63a1\u7528\u3092\u8abf\u67fb\u3002\u5f37\u3044\u63a8\u5968\u306e82\uff05\u3001\u5f31\u3044\u63a8\u5968\u306e61\uff05\u304c\u5404\u56fd\u306eCPG\u3067\u53d6\u308a\u5165\u308c\u3089\u308c\u3066\u3044\u305f\u3002\u5f31\u3044\u63a8\u5968\u3082\u63a1\u7528\u3055\u308c\u308b\u3053\u3068\u306b\u6ce8\u610f\u304c\u5fc5\u8981\u3002<\/p>\n\n\n\n

Alexander PE, Li SA, Gionfriddo MR, Stoltzfus RJ, Neumann I, Brito JP, Djulbegovic B, Montori VM, Schunemann HJ, Guyatt GH: Senior GRADE methodologists encounter challenges as part of WHO guideline development panels: an inductive content analysis. J Clin Epidemiol 2016;70:123-8. PMID: 26385188<\/a>
WHO\u306eCPG\u4f5c\u6210\u306b\u53c2\u52a0\u3057\u305fGRADE\u4e0a\u7d1a\u30e1\u30bd\u30c9\u30ed\u30b8\u30b9\u30c8\u306b\u5bfe\u3059\u308b\u30a4\u30f3\u30bf\u30d3\u30e5\u30fc\u8abf\u67fb\u3002\u30d1\u30cd\u30eb\u30e1\u30f3\u30d0\u30fc\u304cGRADE\u30ac\u30a4\u30c0\u30f3\u30b9\u306b\u5f93\u3046\u3053\u3068\u306b\u62b5\u6297\u3092\u793a\u3057\u7dca\u5f35\u304c\u751f\u3058\u308b\u3002\u3055\u307e\u3056\u307e\u306aCOI\u304c\u4e0d\u6574\u5408\u63a8\u5968\u306b\u5f71\u97ff\u3057\u3066\u3044\u308b\u3001\u30d1\u30cd\u30eb\u306e\u526f\u59d4\u54e1\u9577\u3068\u3057\u3066\u306e\u30e1\u30bd\u30c9\u30ed\u30b8\u30b9\u30c8\u306e\u5f79\u5272\u306e\u660e\u78ba\u5316\u3068\u30b5\u30dd\u30fc\u30c8\u304c\u5fc5\u8981\u3002<\/p>\n\n\n\n

Alexander PE, Gionfriddo MR, Li SA, Bero L, Stoltzfus RJ, Neumann I, Brito JP, Djulbegovic B, Montori VM, Norris SL, Schunemann HJ, Thabane L, Guyatt GH: A number of factors explain why WHO guideline developers make strong recommendations inconsistent with GRADE guidance. J Clin Epidemiol 2016;70:111-22. PMID: 26399903<\/a>
WHO\u306e\u4e0d\u6574\u5408\u63a8\u5968\u306e\u4f5c\u6210\u306b\u95a2\u308f\u3063\u305f\u8005\u306b\u5bfe\u3059\u308b\u30a4\u30f3\u30bf\u30fc\u30d3\u30e5\u30fc\u8abf\u67fb\u306e\u7d50\u679c\u3002\u5f31\u3044\u63a8\u5968\u306f\u7121\u8996\u3055\u308c\u308b\u3053\u3068\u3092\u61f8\u5ff5\u3057\u305f\u306e\u304c\u3072\u3068\u3064\u306e\u7406\u7531\u3002\u307e\u305f\u3001GRADE\u7406\u89e3\u306e\u9650\u754c\u3082\u539f\u56e0\u306e\u4e00\u3064\u3067\u3042\u308a\u3001GRADE\u306e\u539f\u5247\u306b\u30b3\u30df\u30c3\u30c8\u3059\u308b\u8005\u3092\u9078\u629e\u3059\u308b\u3001\u3088\u308a\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3092\u3059\u308b\u3001GRADE\u539f\u5247\u306b\u6cbf\u3063\u3066\u4f5c\u696d\u304c\u9032\u3080\u3088\u3046\u30d5\u30a9\u30fc\u30de\u30eb\u306a\u65b9\u6cd5\u3092\u8003\u3048\u308b\u306a\u3069\u306e\u5bfe\u7b56\u304c\u5fc5\u8981\u3002<\/p>\n\n\n\n

Alexander PE, Brito JP, Neumann I, Gionfriddo MR, Bero L, Djulbegovic B, Stoltzfus R, Montori VM, Norris SL, Schunemann HJ, Guyatt GH: World Health Organization strong recommendations based on low-quality evidence (study quality) are frequent and often inconsistent with GRADE guidance. J Clin Epidemiol 2016;72:98-106. PMID: 25618534<\/a>
WHO\u306f2007\u5e74\u516c\u8846\u885b\u751f\u306eCPG\u306e\u4f5c\u6210\u306bGRADE\u3092\u63a1\u7528\u30022007-2012\u5e74\u306b\u767a\u884c\u3055\u308c\u305fCPG33\u4ef6\u3067160\u500b\u306e\u4e0d\u6574\u5408\u63a8\u5968\uff08C\u307e\u305f\u306fD\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u3067\u5f37\u3044\u63a8\u5968\uff09\u304c\u8a8d\u3081\u3089\u308c\u305f\u300215.6\uff05\u306f\u59a5\u5f53\u300121\uff05\u306f\u6b63\u3057\u304f\u306fB\u307e\u305f\u306fA\u304c\u6b63\u5f53\u5316\u3055\u308c\u308b\u30a8\u30d3\u30c7\u30f3\u30b9\u300118\uff05\u306fGood practice statement\u3067\u300146\uff05\u306f\u5f31\u3044\u63a8\u5968\u304c\u6b63\u5f53\u5316\u3055\u308c\u308b\u3082\u306e\u3067\u3042\u3063\u305f\u3002\u591a\u304f\u304cGRADE guidance\u306b\u5f93\u3063\u3066\u304a\u3089\u305a\u3001\u4f5c\u6210\u8005\u306e\u66f4\u306a\u308b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u304c\u5fc5\u8981\u3002
<\/p>\n","protected":false},"excerpt":{"rendered":"

WHO\u306f\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u4f5c\u6210\u306e\u65b9\u6cd5\u3068\u3057\u3066GRADE\u30a2\u30d7\u30ed\u30fc\u30c1\u30922007\u5e74\u304b\u3089\u63a1\u7528\u3057\u3066\u3044\u307e\u3059\u3002 WHO Handbook for Guideline Development \u306f2nd edition\u304c2014\u5e74\u306b\u767a\u8868\u3055\u308c\u3066 … “WHO Handbook for Guideline Development” \u306e<\/span>\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[],"class_list":["post-369","post","type-post","status-publish","format-standard","hentry","category-cpg"],"_links":{"self":[{"href":"https:\/\/info.zanet.biz\/index.php?rest_route=\/wp\/v2\/posts\/369","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/info.zanet.biz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/info.zanet.biz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/info.zanet.biz\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/info.zanet.biz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=369"}],"version-history":[{"count":2,"href":"https:\/\/info.zanet.biz\/index.php?rest_route=\/wp\/v2\/posts\/369\/revisions"}],"predecessor-version":[{"id":371,"href":"https:\/\/info.zanet.biz\/index.php?rest_route=\/wp\/v2\/posts\/369\/revisions\/371"}],"wp:attachment":[{"href":"https:\/\/info.zanet.biz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=369"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/info.zanet.biz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=369"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/info.zanet.biz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=369"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}