{"id":1878,"date":"2025-09-07T09:07:20","date_gmt":"2025-09-07T00:07:20","guid":{"rendered":"https:\/\/info.zanet.biz\/?p=1878"},"modified":"2025-09-07T09:07:21","modified_gmt":"2025-09-07T00:07:21","slug":"grade-contextulization%e3%81%ab%e3%82%88%e3%82%8b%e5%88%86%e9%a1%9e%e3%81%af%e4%bb%8a%e5%be%8c%e4%bd%bf%e7%94%a8%e3%81%97%e3%81%aa%e3%81%84","status":"publish","type":"post","link":"https:\/\/info.zanet.biz\/?p=1878","title":{"rendered":"GRADE contextulization\u306b\u3088\u308b\u5206\u985e\u306f\u4eca\u5f8c\u4f7f\u7528\u3057\u306a\u3044"},"content":{"rendered":"\n

2025\u5e747\u6708\u306eAnnals of Internal Medicine\u306bSch\u00fcnemann\u6559\u6388\u305f\u3061\u304cGRADE working group\u306e2024\u5e749\u6708\u306e\u6c7a\u5b9a\u4e8b\u9805\u3068\u3057\u3066\u3001\u4eca\u5f8c\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u78ba\u5b9f\u6027\u8a55\u4fa1\u306e\u969b\u306b\u6587\u8108\u5316Contextualization\u306b\u3088\u308b\u6700\u5c0f\u6587\u8108\u5316\u30a2\u30d7\u30ed\u30fc\u30c1Minimally contextualized appproach\u3001\u90e8\u5206\u7684\u6587\u8108\u5316\u306e\u30a2\u30d7\u30ed\u30fc\u30c1Partially contextualized approach\u5b8c\u5168\u6587\u8108\u5316\u306e\u30a2\u30d7\u30ed\u30fc\u30c1Fully contextualized approach\u3068\u3044\u3046\u8a00\u3046\u5206\u985e\u306f\u3084\u3081\u308b\u3053\u3068\u306b\u3057\u305f\u3068\u3044\u3046\u30b7\u30e7\u30fc\u30c8\u30ec\u30dd\u30fc\u30c8\u304c\u51fa\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u5f15\u304d\u7d9a\u304d\u3001\u3088\u308a\u8a73\u7d30\u304c\u8ad6\u6587\u3068\u3057\u3066\u5831\u544a\u3055\u308c\u308b\u305d\u3046\u3067\u3059\u3002<\/p>\n\n\n\n

Hultcrantz M, Sch\u00fcnemann HJ, Mustafa RA, Rind DM, Murad MH, Mayer M, Tovey D, Alper BS, Akl EA, Saif-Ur-Rahman KM, Sousa-Pinto B, Neumann I, Izcovich A, Guyatt G: GRADE Certainty Ratings: Thresholds Rather Than Categories of Contextualization (GRADE Guidance 41). Ann Intern Med 2025;178:1183-1186. doi: 10.7326\/ANNALS-25-00548 PMID: 40587852<\/a><\/p>\n\n\n\n

\u81e8\u5e8a\u306e\u6587\u8108\u3001\u533b\u7642\u74b0\u5883\u306e\u6587\u8108\u3001\u533b\u7642\u8cc7\u6e90\u306e\u6587\u8108\u306a\u3069\u3001\u6587\u8108\u3068\u3044\u308f\u308c\u308b\u3068\u3088\u308a\u60f3\u8d77\u3055\u308c\u3084\u3059\u3044\u5225\u306e\u4e8b\u9805\u304c\u3042\u308b\u305f\u3081\u3001\u6df7\u4e71\u3092\u62db\u304f\u6050\u308c\u304c\u3042\u308b\u304b\u3089\u305d\u3046\u3057\u305f\u3089\u3057\u3044\u3067\u3059\u3002<\/p>\n\n\n\n

\u305f\u3060\u3057\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u78ba\u5b9f\u6027\u8a55\u4fa1\u306e\u65b9\u6cd5\u30fb\u624b\u9806\u304c\u5909\u66f4\u306b\u306a\u3063\u305f\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u5c0f\u30fb\u4e2d\u30fb\u5927\u306e\u6c7a\u65ad\u95be\u5024Decision thresholds\u3092\u8a2d\u5b9a\u3057\u3066\u3001\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u91cd\u8981\u5ea6\u3067\u91cd\u307f\u3065\u3051\u3057\u305f\u52b9\u679c\u63a8\u5b9a\u5024\u306e95%\u4fe1\u983c\u533a\u9593\/\u78ba\u4fe1\u533a\u9593\u306e\u4ea4\u5dee\u306e\u7a0b\u5ea6\u3092\u898b\u3066\u3001\u4e0d\u7cbe\u78ba\u6027Imprecision\u306e\u8a55\u4fa1\u3092\u3059\u308b\u3001\u5fc5\u8981\u306a\u5834\u5408\u306fReview Information Size (RIS)\u3082\u8a55\u4fa1\u3059\u308b\u3068\u3044\u3046\u70b9\u306f\u540c\u3058\u3067\u3059\u3002Imprecision\u3068\u4ed6\u306e\u30c9\u30e1\u30a4\u30f3\u3001\u4f8b\u3048\u3070\u3001\u975e\u4e00\u8cab\u6027Inconsistency, \u30d0\u30a4\u30a2\u30b9\u30ea\u30b9\u30afRisk of bias\u7b49\u3068\u306eInteraction\/\u76f8\u95a2\u95a2\u4fc2\u3092\u8003\u616e\u3057\u3001\u30b0\u30ec\u30fc\u30c9\u30c0\u30a6\u30f3\u306f\u4fdd\u5b88\u7684\u306b\u3001\u3068\u3044\u3046\u306e\u3082\u5909\u308f\u3089\u306a\u3044\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\u300c\u6b63\u5473\u306e\u76ca\u3082\u8003\u616e\u3057\u3066\u6c7a\u65ad\u95be\u5024\u3092\u8a2d\u5b9a\u3057\u305f\u300d\u3001\u300c\u5f53\u8a72\u30a2\u30a6\u30c8\u30ab\u30e0\u3060\u3051\u3092\u8003\u616e\u3057\u3001\u30d1\u30cd\u30eb\u30e1\u30f3\u30d0\u30fc\u306e\u8003\u3048\u306b\u57fa\u3065\u3044\u3066\u95be\u5024\u3092\u8a2d\u5b9a\u3057\u305f\u300d\u3001\u300c\u4ed6\u306e\u30a2\u30a6\u30c8\u30ab\u30e0\u306b\u5bfe\u3059\u308b\u52b9\u679c\u306e\u5927\u304d\u3055\u3068\u78ba\u5b9f\u6027\u3082\u8003\u616e\u3057\u3066\u6c7a\u65ad\u95be\u5024\u3092\u8a2d\u5b9a\u3057\u305f\u300d\u3001\u300c\u5f53\u8a72\u30a2\u30a6\u30c8\u30a6\u30ab\u30e0\u306e\u91cd\u8981\u6027\u306b\u95a2\u3059\u308b\u5831\u544a\u306b\u57fa\u3065\u3044\u3066\u95be\u5024\u3092\u8a2d\u5b9a\u3057\u305f\u300d\u306a\u3069\u3068\u8a18\u8ff0\u3059\u308b\u3053\u3068\u306b\u306a\u308b\u306e\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n

\u4ee5\u524d\u306e\u6295\u7a3f\u300cGRADE\u30a2\u30d7\u30ed\u30fc\u30c1\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u78ba\u5b9f\u6027\u8a55\u4fa1\uff1a3\u7a2e\u985e\u306e\u6587\u8108\u5316\u300d\u306f\u3053\u3061\u3089<\/a>\u3002<\/p>\n\n\n\n

\u95a2\u9023\u6587\u732e\uff1a<\/p>\n\n\n\n

Hultcrantz M, et al: The GRADE Working Group clarifies the construct of certainty of evidence. J Clin Epidemiol 2017;87:4-13. doi: 10.1016\/j.jclinepi.2017.05.006 PMID: 28529184<\/a><\/p>\n\n\n\n

Alper BS, et al: Defining certainty of net benefit: a GRADE concept paper. BMJ Open 2019;9:e027445. doi: 10.1007\/s11882-011-0185-8 PMID: 31167868<\/a>

Zeng L, et al: GRADE guidelines 32: GRADE offers guidance on choosing targets of GRADE certainty of evidence ratings. J Clin Epidemiol 2021;137:163-175. doi: 10.1016\/j.jclinepi.2021.03.026 PMID: 33857619<\/a>

Sch\u00fcnemann HJ, et al: GRADE guidance 35: update on rating imprecision for assessing contextualized certainty of evidence and making decisions. J Clin Epidemiol 2022;150:225-242. doi: 10.1016\/j.jclinepi.2022.07.015 PMID: 35934266<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

2025\u5e747\u6708\u306eAnnals of Internal Medicine\u306bSch\u00fcnemann\u6559\u6388\u305f\u3061\u304cGRADE working group\u306e2024\u5e749\u6708\u306e\u6c7a\u5b9a\u4e8b\u9805\u3068\u3057\u3066\u3001\u4eca\u5f8c\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u78ba\u5b9f\u6027\u8a55\u4fa1\u306e\u969b\u306b\u6587\u8108\u5316Cont … “GRADE contextulization\u306b\u3088\u308b\u5206\u985e\u306f\u4eca\u5f8c\u4f7f\u7528\u3057\u306a\u3044” \u306e<\/span>\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5,2],"tags":[],"class_list":["post-1878","post","type-post","status-publish","format-standard","hentry","category-cpg","category-sr"],"_links":{"self":[{"href":"https:\/\/info.zanet.biz\/index.php?rest_route=\/wp\/v2\/posts\/1878","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/info.zanet.biz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/info.zanet.biz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/info.zanet.biz\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/info.zanet.biz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1878"}],"version-history":[{"count":2,"href":"https:\/\/info.zanet.biz\/index.php?rest_route=\/wp\/v2\/posts\/1878\/revisions"}],"predecessor-version":[{"id":1881,"href":"https:\/\/info.zanet.biz\/index.php?rest_route=\/wp\/v2\/posts\/1878\/revisions\/1881"}],"wp:attachment":[{"href":"https:\/\/info.zanet.biz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1878"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/info.zanet.biz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1878"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/info.zanet.biz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1878"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}