{"id":1482,"date":"2024-03-31T20:33:16","date_gmt":"2024-03-31T11:33:16","guid":{"rendered":"https:\/\/info.zanet.biz\/?p=1482"},"modified":"2025-09-07T08:47:20","modified_gmt":"2025-09-06T23:47:20","slug":"grade%e3%82%a2%e3%83%97%e3%83%ad%e3%83%bc%e3%83%81%e3%81%ae%e3%82%a8%e3%83%93%e3%83%87%e3%83%b3%e3%82%b9%e3%81%ae%e7%a2%ba%e5%ae%9f%e6%80%a7%e8%a9%95%e4%be%a1%ef%bc%9a3%e7%a8%ae%e9%a1%9e%e3%81%ae","status":"publish","type":"post","link":"https:\/\/info.zanet.biz\/?p=1482","title":{"rendered":"GRADE\u30a2\u30d7\u30ed\u30fc\u30c1\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u78ba\u5b9f\u6027\u8a55\u4fa1\uff1a3\u7a2e\u985e\u306e\u6587\u8108\u5316"},"content":{"rendered":"\n

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\u56f32\uff0e\u95be\u5024\u3068\u4fe1\u983c\u533a\u9593\u306e\u95a2\u4fc2\u3068\u30ec\u30fc\u30c8\u30c0\u30a6\u30f3\u3002<\/figcaption><\/figure>\n\n\n\n

\u52b9\u679c\u63a8\u5b9a\u5024\u304c\u5927\u306e\u95be\u5024\u3092\u8d85\u3048\u308b\u3088\u3046\u306a\u3042\u308a\u305d\u3046\u3082\u306a\u3044\u5927\u304d\u306a\u52b9\u679c\u3092\u793a\u3057\u3066\u3044\u308b\u5834\u5408\u3001\u3042\u308b\u3044\u306f\u3001\u308f\u305a\u304b\u307e\u305f\u306f\u5c0f\u3055\u306a\u52b9\u679c\u306e\u5834\u5408\u306b\u3001Review Information Size\uff08RIS\uff09\u30ec\u30d3\u30e5\u30fc\u60c5\u5831\u91cf\u3092\u8a08\u7b97\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002\u5927\u30fb\u4e2d\u30fb\u5c0f\u306e\u95be\u5024\u306b\u5bfe\u3059\u308b\u5fc5\u8981\u306aRIS\u3001\u3059\u306a\u308f\u3061\u305d\u306e\u5927\u304d\u3055\u306e\u52b9\u679c\u3092\u8a3c\u660e\u306b\u5fc5\u8981\u306a\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u3092\u8a08\u7b97\u3057\u3001\u305d\u306e\u7d50\u679c\u3067\u3001\u5b9f\u969b\u306e\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u304c\u2022\u5927\u304d\u306a\u52b9\u679c\u306e\u95be\u5024\u3088\u308a\u5c11\u306a\u3044 \u21d2 \uff13\u30ec\u30d9\u30eb\u30ec\u30fc\u30c8\u30c0\u30a6\u30f3\uff1b\u2022\u4e2d\u7b49\u5ea6\u306e\u52b9\u679c\u306e\u95be\u5024\u3088\u308a\u5c11\u306a\u3044 \u21d2 \uff12\u30ec\u30d9\u30eb\u30ec\u30fc\u30c8\u30c0\u30a6\u30f3\uff1b\u2022\u5c0f\u3055\u306a\u52b9\u679c\u306e\u95be\u5024\u3088\u308a\u5c11\u306a\u3044 \u21d2 \uff11\u30ec\u30d9\u30eb\u30ec\u30fc\u30c8\u30c0\u30a6\u30f3\u3059\u308b\u3053\u3068\u304c\u63d0\u6848\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305f\u3060\u3057\u3001\u52b9\u679c\u63a8\u5b9a\u5024\u306e95\uff05\u4fe1\u983c\u533a\u9593\u306e\u5927\u30fb\u4e2d\u30fb\u5c0f\u306e\u95be\u5024\u3068\u306e\u4ea4\u5dee\u3068\u5408\u308f\u305b\u3066\u614e\u91cd\u306b\u5224\u65ad\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n

OIS\u306f\u81e8\u5e8a\u7684\u306b\u610f\u5473\u306e\u3042\u308b\u52b9\u679c\u63a8\u5b9a\u5024\u3092\u8a3c\u660e\u3059\u308b\u306e\u306b\u5fc5\u8981\u306a\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u3002\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u78ba\u5b9f\u6027\u306e\u8a55\u4fa1\u3067\u3001\u90e8\u5206\u7684\u6587\u8108\u5316\u3042\u308b\u3044\u306f\u5b8c\u5168\u6587\u8108\u5316\u30a2\u30d7\u30ed\u30fc\u30c1\u3092\u7528\u3044\u308b\u5834\u5408\u306f\u3001\u5927\u30fb\u4e2d\u30fb\u5c0f\u306e\u95be\u5024\u3092\u8a2d\u5b9a\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u3001\u305d\u308c\u305e\u308c\u306b\u5bfe\u3059\u308b\u5fc5\u8981\u306a\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u3092\u8a08\u7b97\u3059\u308b\u306e\u3067\u3001RIS\u3068\u3044\u3046\u7528\u8a9e\u3092\u7528\u3044\u308b\u3002OIS: Optimal Information Size\u6700\u9069\u60c5\u5831\u91cf; RIS: Review Information Size\u30ec\u30d3\u30e5\u30fc\u60c5\u5831\u91cf<\/pre>\n\n\n\n
\u95be\u5024\u306e\u8a2d\u5b9a\u306f\u56f0\u96e3\u306a\u8ab2\u984c\u3067\u3059\u304c\u3001\u6b21\u306e\u3088\u3046\u306a\u60c5\u5831\u3092\u6839\u62e0\u3068\u3059\u308b\u3053\u3068\u304c\u63d0\u6848\u3055\u308c\u3066\u3044\u307e\u3059\uff1a
\u2022\u52b9\u7528\u5024\u3068\u7d76\u5bfe\u52b9\u679c\u304b\u3089\u95be\u5024\u3092\u8a2d\u5b9a\u3057\u3066\u3044\u308b\u7814\u7a76\u3092\u53c2\u7167\u3059\u308b\u3002
\u2022\u52b9\u7528\u5024\u306b\u95a2\u3059\u308b\u7814\u7a76\u3092\u53c2\u7167\u3059\u308b\u3002
\u2022\u95be\u5024\u304c\u7528\u3044\u3089\u308c\u305f\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3092\u53c2\u7167\u3059\u308b\u3002
\u2022\u75be\u60a3\u5c02\u9580\u5bb6\u3084\u610f\u601d\u6c7a\u5b9a\u306b\u95a2\u4e0e\u3059\u308b\u5229\u5bb3\u95a2\u4fc2\u8005\u304c\u4f55\u3089\u304b\u306e\u60c5\u5831\uff08\u7d4c\u9a13\u3001\u6587\u732e\u60c5\u5831\uff09\u306b\u57fa\u3065\u3044\u3066\u3001\u52b9\u7528\u5024\u3092\u8003\u3048\u306a\u304c\u3089\u95be\u5024\u3092\u8a2d\u5b9a\u3059\u308b\u3002<\/p>\n\n\n\n
\u307e\u305f\u95be\u5024\u3092\u8a2d\u5b9a\u306f\u3001\u307e\u305a\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u91cd\u8981\u5ea6\u3092\u8a2d\u5b9a\u3057\u3001\u305d\u306e\u5f8c\u306b\u884c\u3046\u3079\u304d\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4ee5\u4e0b\u306e\u70b9\u306b\u7559\u610f\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\uff1a
\u2022\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u91cd\u8981\u5ea6\u3092\u30a8\u30d3\u30c7\u30f3\u30b9\u8a55\u4fa1\u306e\u524d\u306b\u6c7a\u3081\u3066\u304a\u304f\u3002
\u2022\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u91cd\u8981\u5ea6\u3092\u6c7a\u3081\u3066\u304b\u3089\u95be\u5024\u3092\u8a2d\u5b9a\u3059\u308b\u3002
\u2022\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u91cd\u8981\u5ea6\u306b\u95a2\u3059\u308b\u65b0\u77e5\u898b\u304c\u5f97\u3089\u308c\u305f\u3089\u95be\u5024\u3092\u30a2\u30c3\u30d7\u30c7\u30fc\u30c8\u3059\u308b\u3002
\u2022\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u91cd\u8981\u5ea6\u306f\u5c11\u306a\u304f\u3068\u3082\u75be\u60a3\u306b\u7279\u7570\u7684\u3067\u3042\u308a\u3001\u76f8\u5bfe\u7684\u306a\u5024\u306a\u306e\u3067\u3001\u540c\u3058\u30a2\u30a6\u30c8\u30ab\u30e0\u304c\u3069\u306e\u3088\u3046\u306a\u75be\u60a3\u3067\u3082\u540c\u3058\u4fa1\u5024\u3092\u6301\u3064\u308f\u3051\u3067\u306f\u306a\u3044\u3002\u307e\u305f\u3001\u4ecb\u5165\u306b\u3088\u308a\u53d6\u308a\u6271\u3046\u3079\u304d\u30a2\u30a6\u30c8\u30ab\u30e0\u304c\u7570\u306a\u308b\u3053\u3068\u3082\u3042\u308b\u306e\u3067\u3001\u540c\u3058\u75be\u60a3\u3067\u3082\u3001\u4ed6\u306e\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u69cb\u6210\u306b\u3088\u3063\u3066\u540c\u3058\u30a2\u30a6\u30c8\u30ab\u30e0\u3067\u3082\u7570\u306a\u308b\u5024\u3092\u8a2d\u5b9a\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u3046\u308b\u3002\uff10\uff5e\uff11\uff10\uff10\uff08\u3042\u308b\u3044\u306f0\uff5e1.0\uff09\u306e\u5024\u3092\u8a2d\u5b9a\u3059\u308b\u3002<\/p>\n\n\n\n
\u307e\u305f\u9023\u7d9a\u5909\u6570\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u5834\u5408\u306e\u95be\u5024\u306e\u8a2d\u5b9a\u306b\u95a2\u3057\u3066\u306f\u4ee5\u4e0b\u306e\u63d0\u6848\u304c\u3055\u308c\u3066\u3044\u307e\u3059\uff1a
\u2022\u5927\u30fb\u4e2d\u30fb\u5c0f\u306e\u95be\u5024\u306b\u95a2\u3059\u308b\u7d4c\u9a13\u7684\u63a8\u5b9a\u5024\u304c\u3042\u308b\u5834\u5408\u3001\u305d\u308c\u3092\u7528\u3044\u308b\u3002\u4f8b\uff1aChronic Respiratory Questionnaire \uff17\u30dd\u30a4\u30f3\u30c8\u30b9\u30b1\u30fc\u30eb\u306e\u5834\u5408\u30010.5, 1.0, 1.5; Visual Analogue Scale\u306e\u5834\u54086, 10, 14
\u2022Minimal Important Difference (MID)\u306e\u63a8\u5b9a\u5024\u304c\u5f97\u3089\u308c\u308b\u5834\u5408\u3001\u305d\u308c\u3092\u5c0f\u3055\u3044\u52b9\u679c\u306e\u95be\u5024\u3068\u3057\u3066\u7528\u3044\u308b\u3002
\u2022\u6a19\u6e96\u5316\u5e73\u5747\u5024\u5dee\uff08SMD\uff09\u3092\u7528\u3044\u3066\u3001SMD 0.2, 0.5, 0.8\u306b\u95be\u5024\u3092\u8a2d\u5b9a\u3059\u308b\u3002
\u2022\u4f55\u3089\u304b\u306e\u60c5\u5831\u306b\u57fa\u3065\u304f\u5c02\u9580\u5bb6\u306e\u63a8\u5b9a\u5024\u3002<\/p>\n\n\n\n
\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03<\/p>\n\n\n\n
Hultcrantz M 2017\u3067\u8ff0\u3079\u3089\u308c\u3066\u3044\u305f\u5b8c\u5168\u6587\u8108\u5316\u306e\u30a2\u30d7\u30ed\u30fc\u30c1\u306e\u30b9\u30c6\u30c3\u30d7\u306f\u4ee5\u4e0b\u306e\u69d8\u306b\u306a\u308a\u307e\u3059\uff1a<\/p>\n\n\n\n
1.\u7d76\u5bfe\u52b9\u679c\u306e\u5927\u304d\u3055\u3068\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u91cd\u8981\u6027\u306e\u7a4d\u306e\u7dcf\u548c\u3068\u3057\u3066\u6b63\u5473\u306e\u76ca\u3092\u8a08\u7b97\u3059\u308b\uff08Alper BS 2019\uff09\u3002
2.\u5404\u30a2\u30a6\u30c8\u30ab\u30e0\u306b\u5bfe\u3059\u308b\u7d76\u5bfe\u52b9\u679c\u306e\u4e0a\u9650\u5024\u3068\u4e0b\u9650\u5024\u3067\u6b63\u5473\u306e\u76ca\u304c\u9006\u8ee2\u3059\u308b\u304b\u3092\u898b\u308b\u3002\uff08\u9006\u8ee2\u306e\u95be\u5024\u306f\uff10\u307e\u305f\u306f\u8a55\u4fa1\u8005\u304c\u8a2d\u5b9a\u3057\u305f\u5024\uff09\u3002
3.\u9006\u8ee2\u3059\u308b\u5834\u5408\u306f\u3001\u305d\u306e\u30a2\u30a6\u30c8\u30ab\u30e0\u306b\u5bfe\u3059\u308b\u52b9\u679c\u306e\u4e0d\u7cbe\u78ba\u6027\u3092\u30ec\u30fc\u30c8\u30c0\u30a6\u30f3\u3057\u3001\uff08\u4ed6\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u78ba\u5b9f\u6027\u8a55\u4fa1\u30c9\u30e1\u30a4\u30f3\u3068\u5408\u308f\u305b\u3066\uff09\u30a8\u30d3\u30c7\u30f3\u30b9\u7dcf\u4f53\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u78ba\u5b9f\u6027\u3092\u30ec\u30fc\u30c8\u30c0\u30a6\u30f3\u3059\u308b\u3002

\u306a\u304a\u3001\u9023\u7d9a\u5909\u6570\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u5834\u5408\u306f\u305d\u306e\u307e\u307e\u3067\u306f\u6b63\u5473\u306e\u76ca\u306e\u8a08\u7b97\u306b\u542b\u3081\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n\n\n\n
\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03\uff03<\/p>\n\n\n\n
Sch\u00fcnemann HJ 2022\u306e\u8ad6\u6587\u3067\u8ff0\u3079\u3089\u308c\u3066\u3044\u308b\u5b8c\u5168\u6587\u8108\u5316\u306e\u30a2\u30d7\u30ed\u30fc\u30c1\u306e\u30b9\u30c6\u30c3\u30d7\u306f\u4ee5\u4e0b\u306e\u69d8\u306b\u306a\u308a\u307e\u3059\uff1a<\/p>\n\n\n\n
0.  \u90e8\u5206\u7684\u6587\u8108\u5316\u30a2\u30d7\u30ed\u30fc\u30c1\u3067\u5404\u30a2\u30a6\u30c8\u30ab\u30e0\u306b\u5bfe\u3059\u308b\u52b9\u679c\u63a8\u5b9a\u5024\u306e\u4e0d\u7cbe\u78ba\u6027\u306e\u8a55\u4fa1\u3092\u884c\u3046\u3002
1.\u76ca\u306e\u30a2\u30a6\u30c8\u30ab\u30e0\u306b\u5bfe\u3059\u308b\u52b9\u679c\u63a8\u5b9a\u5024\u306e95\uff05\u4fe1\u983c\u533a\u9593\u4e0b\u9650\u5024\u306b\u57fa\u3065\u3044\u3066\u3042\u308a\u3046\u308b\u6700\u5c0f\u306e\u671b\u307e\u3057\u3044\u7d76\u5bfe\u52b9\u679c\u91cf\u3092\u7279\u5b9a\u3059\u308b\u3002
2.\u5bb3\u306e\u30a2\u30a6\u30c8\u30ab\u30e0\u306b\u5bfe\u3059\u308b\u52b9\u679c\u63a8\u5b9a\u5024\u306e95\uff05\u4fe1\u983c\u533a\u9593\u4e0a\u9650\u5024\u306b\u57fa\u3065\u3044\u3066\u3042\u308a\u3046\u308b\u6700\u5927\u306e\u671b\u307e\u3057\u304f\u306a\u3044\u7d76\u5bfe\u52b9\u679c\u91cf\u3092\u7279\u5b9a\u3059\u308b\u3002
3.\u6700\u5c0f\u306e\u671b\u307e\u3057\u3044\u52b9\u679c\u3092\u96c6\u7d04\uff08aggregate\uff09\u3057\u3001\u305d\u308c\u306b\u57fa\u3065\u3044\u3066\u4ecb\u5165\u3092\u63a8\u5968\u3059\u308b\u306e\u306b\u8a31\u5bb9\u3057\u3046\u308b\u6700\u5927\u306e\u3042\u308a\u3046\u308b\u671b\u307e\u3057\u304f\u306a\u3044\u52b9\u679c\u306e\u7dcf\u548c\uff08overall\uff09\u3092\u6c7a\u3081\u308b\uff08\u5fc5\u8981\u306b\u5fdc\u3058\u3066\u8cbb\u7528\u306a\u3069\u3082\u8003\u616e\u3059\u308b\uff09\u3002\u500b\u3005\u306e\u671b\u307e\u3057\u304f\u306a\u3044\u30a2\u30a6\u30c8\u30ab\u30e0\u306b\u5bfe\u3059\u308b\u52b9\u679c\u306e\u3042\u308a\u3046\u308b\u6700\u5927\u5024\u306b\u57fa\u3065\u3044\u3066\u4e0d\u7cbe\u78ba\u6027\u306e\u30ec\u30fc\u30c6\u30a3\u30f3\u30b0\u3092\u5909\u66f4\u3059\u308b\u5fc5\u8981\u304c\u3042\u308b\u304b\u3092\u6c7a\u3081\u308b\u306e\u306b\u3053\u306e\u7dcf\u548c\u306e\u95be\u5024\u3092\u8003\u616e\u3059\u308b\u3002\u8907\u6570\u306e\u671b\u307e\u3057\u304f\u306a\u3044\u52b9\u679c\u304c\u3042\u308b\u5834\u5408\u3001\u3053\u308c\u3092\u5404\u30a2\u30a6\u30c8\u30ab\u30e0\u306b\u3064\u3044\u3066\u500b\u5225\u306b\u3001\u3042\u308b\u3044\u306f\u96c6\u7a4d\u3057\u305f\u4e0a\u3067\u3001\u884c\u308f\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u3053\u3068\u306b\u7559\u610f\u3059\u308b\u3002
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\u6587\u732e\uff1a<\/strong>
Hultcrantz M, et al: The GRADE Working Group clarifies the construct of certainty of evidence. J Clin Epidemiol 2017;87:4-13. doi: 10.1016\/j.jclinepi.2017.05.006 PMID: 28529184<\/a><\/p>\n\n\n\n
Alper BS, et al: Defining certainty of net benefit: a GRADE concept paper. BMJ Open 2019;9:e027445. doi: 10.1007\/s11882-011-0185-8 PMID: 31167868<\/a>

Zeng L, et al: GRADE guidelines 32: GRADE offers guidance on choosing targets of GRADE certainty of evidence ratings. J Clin Epidemiol 2021;137:163-175. doi: 10.1016\/j.jclinepi.2021.03.026 PMID: 33857619<\/a>

Sch\u00fcnemann HJ, et al: GRADE guidance 35: update on rating imprecision for assessing contextualized certainty of evidence and making decisions. J Clin Epidemiol 2022;150:225-242. doi: 10.1016\/j.jclinepi.2022.07.015 PMID: 35934266<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"
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