{"id":1392,"date":"2023-07-06T08:21:57","date_gmt":"2023-07-05T23:21:57","guid":{"rendered":"https:\/\/info.zanet.biz\/?p=1392"},"modified":"2023-07-25T13:38:54","modified_gmt":"2023-07-25T04:38:54","slug":"pragmatic-clinical-trial%e3%83%97%e3%83%a9%e3%82%b0%e3%83%9e%e3%83%86%e3%82%a3%e3%83%83%e3%82%af%e8%87%a8%e5%ba%8a%e8%a9%a6%e9%a8%93","status":"publish","type":"post","link":"https:\/\/info.zanet.biz\/?p=1392","title":{"rendered":"Pragmatic Clinical Trial\u30d7\u30e9\u30b0\u30de\u30c6\u30a3\u30c3\u30af\u81e8\u5e8a\u8a66\u9a13"},"content":{"rendered":"\n

\u30d7\u30e9\u30b0\u30de\u30c6\u30a3\u30c3\u30af\u81e8\u5e8a\u8a66\u9a13\u306f\u3055\u307e\u3056\u307e\u306b\u5b9a\u7fa9\u3055\u308c\u3066\u304a\u308a\u3001\u7d71\u4e00\u3055\u308c\u305f\u5b9a\u7fa9\u306f\u3042\u308a\u307e\u305b\u3093\u304c\u3001\u4f8b\u3048\u3070\u3001Califf\u3068Sugarman\u306f\u3001\u300c\u4ecb\u5165\u306e\u76ca\u3001\u8ca0\u62c5\u3001\u5bb3\u306e\u30d0\u30e9\u30f3\u30b9\u306b\u3064\u3044\u3066\u610f\u601d\u6c7a\u5b9a\u8005\u306b\u60c5\u5831\u3092\u4e0e\u3048\u308b\u3053\u3068\u3092\u4e3b\u306a\u76ee\u7684\u3068\u3057\u3066\u30c7\u30b6\u30a4\u30f3\u3055\u308c\u305f\u7814\u7a76\u300d\u3068\u5b9a\u7fa9\u3057\u3066\u3044\u307e\u3059\uff0e\u6bd4\u8f03\u52b9\u679c\u7814\u7a76\u306b\u5305\u542b\u3055\u308c\u308b\u3088\u3046\u306a\u5b9a\u7fa9\u3067\u3059\uff0e<\/p>\n\n\n\n

\u7279\u306b\u91cd\u8981\u3068\u601d\u308f\u308c\u308b\u7279\u5fb4\u306f\u300c\u73fe\u5b9f\u7684\u306a\u72b6\u6cc1\u4e0b\u3067\u306e\u52b9\u679c\u3092\u8a3c\u660e\u3059\u308b\u300d\u3053\u3068\u304c\u8003\u3048\u3089\u308c\u307e\u3059\uff0e\u8a00\u3044\u63db\u3048\u308b\u3068\u5b9f\u7528\u6027\u304c\u9ad8\u3044\u81e8\u5e8a\u8a66\u9a13\u3068\u3082\u8a00\u3048\u307e\u3059\uff08\u56f31\uff09\uff0e<\/p>\n\n\n\n

\"\"
\u56f31. Pragmatic Clinical Trials \u30d7\u30e9\u30b0\u30de\u30c6\u30a3\u30c3\u30af\u81e8\u5e8a\u8a66\u9a13\u3002\u4eca\u5f8cICT\u3092\u5229\u7528\u3057\u3066\u3001\u591a\u9762\u7684\/\u5168\u4eba\u7684\u3067\u9023\u7d9a\u7684\u306a\u500b\u4eba\u306e\u30d3\u30c3\u30b0\u30c7\u30fc\u30bf\u3092\u53ce\u96c6\u3057\u3066\u5373\u6642\u89e3\u6790\u304c\u884c\u308f\u308c\u308b\u3088\u3046\u306b\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u3001\u30d7\u30e9\u30b0\u30de\u30c6\u30a3\u30c3\u30af\u81e8\u5e8a\u8a66\u9a13\u304c\u4e00\u822c\u5316\u3059\u308b\u53ef\u80fd\u6027\u304c\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/figcaption><\/figure>\n\n\n\n

\u307e\u305f\u3001Pragmatic-explanatory continuum indicator summary (PRECIS)\u3068\u547c\u3070\u308c\u308b\u3001\u81e8\u5e8a\u8a66\u9a13\u3092\u8a55\u4fa1\u3059\u308b\u30c4\u30fc\u30eb\u304c\u4f5c\u6210\u3055\u308c\u3066\u3044\u307e\u3059\uff08\u56f32\uff09\uff0e<\/p>\n\n\n\n

\"\"
\u56f32. \u30d7\u30e9\u30b0\u30de\u30b9\u30b3\u30fc\u30d7\u306e\u4e00\u3064\u3067\u3042\u308bPragmatic-explanatory continuum indicator summary (PRECIS)\u300210\u500b\u306e\u30af\u30e9\u30a4\u30c6\u30ea\u30a2\u304b\u3089\u81e8\u5e8a\u8a66\u9a13\u306e\u5b9f\u7528\u6027\u3092\u8a55\u4fa1\u3057\u307e\u3059\u3002<\/figcaption><\/figure>\n\n\n\n

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\u4f8b\u3048\u3070\u3001\u53c2\u52a0\u8005\u306e\u9069\u683c\u57fa\u6e96\u3067\u3001\u30b3\u30f3\u30d7\u30e9\u30a4\u30a2\u30f3\u30b9\u304c\u4f4e\u3044\u3068\u601d\u308f\u308c\u308b\u4eba\u306f\u9664\u5916\u3059\u308b\u3001\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u30ea\u30b9\u30af\u304c\u4f4e\u3044\u3068\u601d\u308f\u308c\u308b\u4eba\u306f\u9664\u5916\u3059\u308b\u3001\u53c2\u52a0\u8005\u304c\u72ed\u3044\u7bc4\u56f2\u304b\u3089\u52df\u96c6\u3055\u308c\u3066\u3044\u308b\u3001\u3053\u308c\u3089\u306f\u52b9\u679c\u306e\u8a3c\u660e\u306b\u306f\u6709\u5229\u306b\u50cd\u304d\u307e\u3059\u3051\u308c\u3069\u3082\u3001\u5b9f\u7528\u6027\u306f\u4f4e\u304f\u306a\u308a\u307e\u3059\uff0e \u3064\u307e\u308a \u5b9f\u4e16\u754c\u3067\u69d8\u3005\u306a\u5bfe\u8c61\u8005\u306b\u4f7f\u7528\u3055\u308c\u305f\u5834\u5408\u3001\u4e88\u60f3\u3055\u308c\u308b\u52b9\u679c\u304c\u5f97\u3089\u308c\u306a\u3044\u53ef\u80fd\u6027\u304c\u9ad8\u304f\u306a\u308a\u307e\u3059\uff0e<\/p>\n\n\n\n

\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u306f\u591a\u304f\u306e\u5834\u5408\u3001\u6cbb\u7642\u306e\u52b9\u679c\u3092\u8a3c\u660e\u3057\u3084\u3059\u3044\u3088\u3046\u306b\u8a2d\u8a08\u3055\u308c\u3066\u3044\u307e\u3059\uff0e\u8a00\u3044\u63db\u3048\u308b\u3068\u6cbb\u7642\u52b9\u679c\u3092\u8a3c\u660e\u3059\u308b\u306e\u306b\u6700\u9069\u306b\u306a\u308b\u3088\u3046\u306b\u3055\u307e\u3056\u307e\u306a\u6761\u4ef6\u304c\u8a2d\u5b9a\u3055\u308c\u3066\u3044\u307e\u3059\uff0e\u305d\u306e\u305f\u3081\u3001\u793a\u3055\u308c\u305f\u52b9\u679c\u306e\u5927\u304d\u3055\u304c\u4e00\u822c\u7684\u306a\u72b6\u6cc1\u3067\u305d\u306e\u307e\u307e\u518d\u73fe\u3055\u308c\u308b\u3068\u306f\u9650\u308a\u307e\u305b\u3093\uff0e\u305d\u306e\u3088\u3046\u306a\u81e8\u5e8a\u8a66\u9a13\u306fExplanatory trials\u8aac\u660e\u7684\u81e8\u5e8a\u8a66\u9a13\u3042\u308b\u3044\u306f\u3001\u52b9\u679c\u3092\u8a3c\u660e\u3057\u3084\u3059\u3044\u3088\u3046\u6700\u9069\u5316\u3055\u308c\u3066\u3044\u308b\u3068\u3044\u3046\u610f\u5473\u3067\u6700\u9069\u6761\u4ef6\u8a66\u9a13\u306a\u3069\u3068\u3082\u547c\u3070\u308c\u3066\u3044\u307e\u3059\uff08\u56f33\uff09\u3002<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

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\u6587\u732e\uff1a<\/strong>
Califf RM, Sugarman J: Exploring the ethical and regulatory issues in pragmatic clinical trials. Clin Trials 2015;12:436-41. doi: 10.1177\/1740774515598334 PMID: 26374676<\/a>

Ford I, Norrie J: Pragmatic Trials. N Engl J Med 2016;375:454-63. doi: 10.1056\/NEJMra1510059 PMID: 27518663<\/a>

\u533b\u85ac\u54c1\u8a55\u4fa1\u59d4\u54e1\u4f1a Pragmatic Trials\u306e\u30b9\u30b9\u30e1 – \u65e5\u672c\u88fd\u85ac\u5de5\u696d\u5354\u4f1a. Link<\/a>

Thorpe KE, et al: CMAJ 2009;180:E47-57. doi: 10.1503\/cmaj.090523 PMID: 19372436<\/a>

Tosh G, et al: Pragmatic vs explanatory trials: the pragmascope tool to help measure differences in protocols of mental health randomized controlled trials. Dialogues Clin Neurosci 2011;13:209-15. doi: 10.31887\/DCNS.2011.13.2\/gtosh PMID: 21842618<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

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